INTERNATIONAL PHARMA CONSULTING

Good pharma? Bad pharma? Better pharma.

International Journal of Pharma Research 5(3):29-38

Biotechnology revolution had led the overcoming of different types of therapeutic protein because of their chemical structure can perform specific reactions in the body, increasing efficacy and decreasing side effects. Numerous efforts were made to optimize the physicochemical properties of the proteins used for therapeutic and studied different methods for an effective administration of the pr...

International Journal of Pharma Research 5(4):29-33

In current healthcare provision there is an ever growing focus on acquisition cost of pharmacological interventions, and whether they represent value for money. It is often forgotten that for every “breakthrough” drug that makes it onto our formularies, approximately 1000 never get beyond phase 1 clinical trials. Even once this hurdle is passed, there are many more obstacles that stand in the w...

International Journal of Pharma Research 5(3):51-58

Regulation of pH is critical for physiological processes. Maintenance of acid-base homeostasis is tightly regulated by the renal and respiratory systems. However, fluctuations in extracellular pH are also sensed by other organ systems. Ion transporter activity to modify the amount of acid (H+ and CO2) and bicarbonate HCO3 is therefore actively maintained within the kidney and lung. This review ...

International Journal of Pharma Research 5(8):13-18

Recombinant gene expression has been the most commonly used method to obtain large quantity of proteins such as enzymes and antigens for pharmaceutical and clinical applications. Although many genes have been efficiently expressed in Escherichia coli, low level of expression and inclusion body formation are still a bottle-neck problem in desired protein production. The expression vectors pHsh a...